Abstract

AimFatigue is one of the most commonly reported symptoms of MS. This trial evaluates the clinical effectiveness of a group-based fatigue management intervention for people with MS.Study designPragmatic multi-centre parallel...

Highlights

  • Fatigue is one of the most commonly reported and debilitating symptoms of multiple sclerosis (MS); approximately two-thirds of people with MS consider it to be one of their three most troubling symptoms

  • This trial is the fourth stage of a research programme that has followed the Medical Research Council guidance for developing and evaluating complex interventions

  • A potential strength of the intervention is that it could be integrated into existing service delivery models as it has been designed to be delivered by staff already working with people with MS

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Summary

Introduction

Fatigue is one of the most commonly reported and debilitating symptoms of multiple sclerosis (MS); approximately two-thirds of people with MS consider it to be one of their three most troubling symptoms. It may limit or prevent participation in everyday activities, work, leisure, and social pursuits, reduce psychological well-being and is one of the key precipitants of early retirement. Multiple sclerosis (MS) is a chronic, unpredictable, incurable, demyelinating disease of the central nervous system affecting approximately 2.5 million people [1,2,3]. Findings on the relationships between fatigue and other clinical variables (such as age, gender, disease duration, and clinical activity) have been equivocal [11]

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