Abstract
Introduction: mechanical ventilation is a necessarytherapy in critical pathologies with respiratory failure, producing acute pulmonary injury. Objectives: To identify an acute pulmonary injuryby bronchioalveolar lavage cytology and determinecausal relations with the Fraction of inspired Oxygen(FiO2), the pressure of the airways, positive endexpiratorypressure (PEEP), oxygen saturation andexposure time. Methods: Longitudinal, prospective clinicalinvestigation from January to July 2007, whichincluded 51 patients that received mechanicalventilation. 153 bronchioalveolar lavage citologieswere obtained and processed. Results: Several alterations in citologies wereobserved at 12, 72 and 144 hours after mechanicalventilation was started, which shows a simpleand meaningful statistic association with fractionof given oxygen at 12 and 74 hours, PEEP at 12hours, Pressure in air ways and and oxygen. Discussion: It becomes evident that alterationsproduced by mechanical ventilation are connectedwith FiO2, oxygen saturation, absence or low PEEPand elevated airway pressure. Conclusion: Alterations in citologies of thebronchioalveolar epithelium present themselves inthe presence of FiO2 and low PEEP.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
