1295 A National Population-Based Survey of the Prevalence, Potential Risk Factors, and Symptom-Specific Bother in Symptomatic Pelvic Organ Prolapse in Adult Chinese Women–Pelvic Organ Prolapse Quantification System Based Study

Abstract

Study Objective To provide estimates of the prevalence and potential risk factors associated with pelvic organ prolapse (POP) based on Pelvic Organ Prolapse quantification (POP-Q) system and the bother it imposes in a nationwide population-based sample of adult women in China. Design A national cross-sectional study from February 2014 through March 2016. Setting Mainland China. Patients or Participants A nationally representative sample of 54,000 adults who were 20 years old or older were sampled using multi-stage, stratified, cluster sampling at six populous provinces in mainland China among participants of National Mass Screening on Breast and Cervical Cancers. Interventions No interventions were conducted. Measurements and Main Results POP was assessed using POP-Q stage and validation questionnaires. Multivariable logistic regression was used to assess factors associated with each degree or bother POP. The prevalence of symptomatic POP (POP-Q stage II or higher) was 9.56%. Stage II POP was the most common (7.52%) and mainly involved anterior compartment. Incidence increased with age for all stages (P≤0.05). Minor or moderate bother were the most common responses that were reported for every stage of POP (9.72%). Only 0.08% of the participants reported that the condition had a severe impact on their quality of life. Older age, postmenopausal status, and multiple vaginal deliveries increased the odds of every kind of POP (p ≤ 0.05). Conclusion Based on physical objective examination, our study yielded a Lower prevalence than that in other surveys and mainly involved anterior compartment, which suggests that it should be considered for medical intervention. Older age, postmenopausal status, and multiple vaginal deliveries increased the odds of every kind of POP.