Abstract

Lymphomas represent a very heterogeneous group of hematological malignancies and, despite successful therapies, they are a major challenge in clinical practice. Lymphomas often develop resistance to treatment with standard of care drugs (SoC) and have a high relapse rate. Therefore, new therapies are needed to improve long-term remission and patient survival. Recent advances in high-throughput molecular profiling have helped to identify genetic factors and genetic subtypes of diffuse large B-cell lymphoma (DLBCL).

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