Abstract
Purpose The aim of the study was to compare the accuracy of longitudinal diastolic velocity and strain rate (SR) obtained by tissue Doppler imaging (TDI), 2D and 3D speckle tracking in assessing left ventricular end diastolic pressure (LVEDP) Methods LVEDP measurements were performed in 40 consecutive patients referred for coronary angiogram (mean age = 60 ± 15 years, mean EF = 41 ± 14%). A comprehensive transthoracic echocardiography (Artida, Toshiba) study was performed immediately after LVEDP measurement. Echocardiography data acquired included mitral early diastolic velocity (E) by conventional pulsed Doppler, early diastolic mitral annulus velocity by TDI (E’), and high frame rate 2 and 3D apical views. Global longitudinal SR by 2D (2DEGSR) and 3D (3DEGSR) were assessed using longitudinal strain curves from speckle tracking analysis. LV filling pressure estimated using echocardiography data (E/E’, E/2DE GSR, E/3DE GSR) were correlated to invasive LVEDP measurements. Result On the whole, LVEDP averaged 13 mmHg (5 to 32,) and best correlated with LV filling pressure assessed by 2D speckle tracking (r2 = 0.65, p Conclusions Longitudinal diastolic strain rate by 2D and not 3D speckle tracking appears superior to conventional E/E’ by TDI for assessing LV filling pressure. Download : Download full-size image
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