Abstract
The aim of our study was to detect the association between cytokines that are essential for bone health, e.g. osteoprotegerin (OPG), s-RANKL and markers of nutritional status, e.g. somatomedin I (IgF I), leptin in malnourished infants. The study comprised of 86 infants (42 boys and 44 girls) between the 4th and 7 th months of age. According to their position of body weight and BMI at percentile charts for sex and age two groups were created: group I consisted of 54 malnurished infants with body weight and BMI (11.9) 0.05). Statistical difference was confirmed for the level of leptin and s-RANKL between groups I and II (p < 0.001, p < 0.05 respectively). In malnourished infants (group I) statistically significant correlation was detected between the level of s-RANKL and IGF I (r = 0.39, p < 0.05). Conclusion: Results of our study confirmed that malnutrition may influence bone metabolism in infants.
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