Abstract
Objectives This study was conducted assess the relation between alteration of the amino acids profile and plasma albumin in preeclampsia. Methods We performed a cross sectional study using 10 patients with preeclampsia albumin ⩽3 gr/dL and 9 patients with preeclampsia albumin >3 gr/dL. Plasma albumin was analyzed by photometric using Dyalis reagent, and plasma amino acids were analyzed by ion exchange chromatography (IEC). Results There were alterations of amino acids in patients with an albumin ⩽ 3 gr/dL compare with those with an albumin >3 gr/dL. Essential amino acids and non-essential amino acids were significantly different (Hotteling T0.05). Regression analysis revealed that 94% of the alteration of 10 amino acids influenced albumin concentration. Conclusions Alteration of the plasma amino acid profile influenced albumin concentration in preeclampsia. Plasma albumin changes were influenced by more than one amino acids rather than single. Disclosures A. Aditiawarman: None. E.G. Dachlan: None.
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