Abstract

Computational modelling method is an important technique to better understand bone mechanical properties and the relationship between bone structure and its mechanical, as well as biological environment. The chapter first introduces three distinct computational modelling examples of bone, i.e., subject-specific quantitative computed tomography (QCT) image-based nonlinear finite element modelling of proximal femur for bone strength estimation, microfinite element modelling for trabecular bone yield behaviors at the tissue level, and dynamic modelling for the mechanical behaviors of trabecular bone in the intertrochanteric fracture fixation. It then describes computational simulations of bone remodelling and adaptation of trabecular bone to mechanical and biological factors.

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