Abstract
The atypical skin lesions are a diverse group of tumors that are uncommon but clinically important. They include a spectrum from benign lesions through to those that demonstrate local invasion and/or distant metastatic potential. Since these lesions are only seen infrequently during clinical practice, it is important to have a solid grounding in the general principles of their management. The chapter also covers some common surgically relevant lesions of the skin, including common types of cysts. A clear understanding of cysts and their etiology is important to direct their management. The chapter divides the atypical lesions into benign or malignant and then by their cell/tissue of origin to provide a framework for their study. Such a framework is not perfect due to our evolving understanding of the molecular and cellular bases of these tumors, but it provides a foundation for their study.
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