Abstract
The asymmetric unit of the title compound, C16H14N2O, contains three independent molecules differing primarily in the orientations of the benzyl groups. Each independent molecule forms inversion related dimersviaoffset π-stacking interactions. For two of these dimers, stacks are formed approximately along thea-axis direction by a combinations of C—H...N and C—H...π(ring) contacts, in addition to the offset π-stacking interactions. The third set of dimers are also stacked in the same direction but only by pairwise C—H...N hydrogen bonds.
Highlights
The asymmetric unit of the title compound, C16H14N2O, contains three independent molecules differing primarily in the orientations of the benzyl groups
The third set of dimers are stacked in the same direction but only by pairwise C—HÁ Á ÁN hydrogen bonds
Quinoxaline derivatives have a special place in medicinal chemistry and are commonly present in the bioactive molecules used in many therapeutic areas (Kour et al, 2013)
Summary
Quinoxaline derivatives have a special place in medicinal chemistry and are commonly present in the bioactive molecules used in many therapeutic areas (Kour et al, 2013). Compounds containing the quinoxaline moiety show a wide range of biological activities including anti-inflammatory, analgesic, and antidepressant effects. They demonstrate antifungal, antibacterial, antimalarial, antitubercular, anticancer, antidiabetic, anticonvulsant, antianxiety, and metal-binding properties (Rohde et al, 2016; Wang et al, 2007; Berubeet al., 2015; Ramli & Essassi, 2015). The C1—N2— C10—C11, the C17—N4—C26—C27 and the C33—N6—C42—C43 torsion angles are, respectively, 75.76 (13), 76.68 (13) and À82.29 (13). Each independent molecule forms a stack, with each stack oriented approximately along the a-axis direction (Fig. 2). Cg2, Cg3, Cg6, Cg7 and Cg11 are the centroids of the C1–C6, C11–C16, C17– C22, C27–C32 and C43–C48 benzene rings, respectively
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
