Abstract

Abstract Introduction To explore the prevalence and risk factors of obstructive sleep apnea syndrome (OSAS) in 3-14 years old children in Beijing. Methods A cross-sectional study of random stratified cluster sampling was conducted on 3-14 years old children and adolescents in Beijing. The preliminary screening was completed through Pediatric Sleep Questionnaire (PSQ) investigation and the diagnosis of OSAS was conducted by polysomnography. Results After random sampling, a total of 11 kindergartens, 7 primary schools and 8 junior high schools from 7 districts of Beijing were involved in the survey. A total of 11420 questionnaires were sent out, and 10743 (94.07%) were recovered. The final effective data were 9198 (effective response rate 85.62%). The age of the investigated children was 8.8±3.8 years. PSQ positive rate was 8.86% (95CI 8.28-9.44%). With diagnostic criteria AHI≥5, the estimated prevalence of OSAS in Beijing children was 5.90% (95%CI 3.72-8.28%); with ICSD-3 diagnostic criteria (OAHI>1), the estimated prevalence was 8.08% (95% CI 5.74-10.62%). Overweight (OR=3.13), frequent allergic rhinitis (OR=6.80) and family snoring history (OR=6.14) were important risk factors for children’s OSAS. Conclusion PSQ was used in Beijing children’s OSAS epidemiological survey with good reliability and validity. The positive rate of the PSQ screening was 8.86% (95CI 8.28-9.44%);the estimated prevalence of OSAS in children aged 3-14 years in Beijing was 5.90% (95%CI 3.72-8.28%) with criteria AHI≥5 and 8.08% (95%CI 5.74-10.62%) with criteria OAHI>1, respectively. Gender, BMI, history of ENT and family history of snoring were important risk factors for children’s OSAS. Support This work was supported by Beijing Municipal Science and Technology Project grant (Z161100000116050 and Z161100003216212) and Beijing Municipal Administration of Hospitals Clinical Technology Innovation Project grant (XMLX201701).

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