0470 CHARACTERIZING ADULTS WITH OBSTRUCTIVE SLEEP APNEA WHO REPORT NOCTURNAL ENURESIS

Abstract

Obstructive sleep apnea (OSA) is known to associate with nocturnal enuresis (NE) in children, and it has been shown that treatment of OSA may lead to resolution of NE in this population. In contrast, the association between OSA and NE in adults remains the subject of a handful of case reports and series. To characterize this relationship, we studied a population of adults diagnosed with OSA by polysomnography (PSG) at Boston Medical Center. A database containing a subset of 84 patients out of 351 referred for PSG for evaluation of OSA was analyzed for differences between patients who reported NE and those who denied it on initial screening. The subset of patients included in the analysis met diagnostic criteria for OSA, and reported some degree of nocturia, if they did not report NE. T-tests and Chi-square analyses were used to determine differences between those with and without NE with respect to demographics, comorbidities, medications, and PSG measures. Of 351 individuals referred for PSG for evaluation of OSA, 4.0% reported NE. Of those 84 with OSA included in the analysis, NE patients were more likely to be older (p < 0.05), and more likely to have hypertension (p < 0.05) and prior stroke (p < 0.05). A trend was observed in which NE patients were more likely to be prescribed an opioid or benzodiazepine (p = 0.07). There were no differences with respect to PSG measures. NE is an uncommon complaint among individuals referred for PSG for OSA screening, but may be more common among those ultimately diagnosed with OSA, and we provide evidence that it may associate with age, comorbidities, and certain medications. In light of anecdotal evidence that continuous positive airway pressure therapy may alleviate NE in adults with confirmed OSA, routine screening for NE in patients referred for PSG may aid in diagnosis and treatment of this burdensome condition. None.