003 Is Vitamin D3 an Independent Marker of Endothelial Dysfunction?

Abstract

Vitamin D deficiency has emerged as a risk factor in a range of condition, from diabetes to hypertension, and heart disease all of which are related to ED. Endothelial dysfunction has been demonstrated to play an important role in pathogenesis of erectile dysfunction (ED) and vitamin D deficiency is deemed to promote endothelial dysfunctions. Low levels of vitamin D are significantly and independently associated with low levels of testosterone in otherwise healthy middle-aged men which can also be a reason for ED. To assess serum vitamin D3 levels in patients with erectile dysfunction and also to correlate vitamin D3 levels with severity of endothelial dysfunction. 90 Patients presenting to OPD with complaints of erectile dysfunction were assessed based on history and clinical examination. Once the diagnosis was confirmed, IIEF- 5 was administered by the doctor himself based on which the severity of ED was graded. The degree of endothelial dysfunction in these patients was measured by using VENDYS (endothelial function test) and the vascular reactivity index was noted. Serum Vitamin D3 levels were assessed in all of these patients following which the values were statistically analyzed with vascular reactivity index and then correlated.