Abstract
Shuhtin V. V., Sknar V. N., Shuhtina I. N., Zukow W. Роль некоторых биохимических показателей у больных хроническим простатитом = The role of some biochemical parameters in patients with chronic prostatitis. Journal of Education, Health and Sport. 2016;6(2):11-17. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.45485 http://ojs.ukw.edu.pl/index.php/johs/article/view/3373 https://pbn.nauka.gov.pl/works/711693 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015). 755 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author (s) 2016; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 01.01.2016. Revised 12.01.2016. Accepted: 31.01.2016. УДК 616.699:616.697-07:616.69-008.8-097 РОЛЬ НЕКОТОРЫХ БИОХИМИЧЕСКИХ ПОКАЗАТЕЛЕЙ У БОЛЬНЫХ ХРОНИЧЕСКИМ ПРОСТАТИТОМ THE ROLE OF SOME BIOCHEMICAL PARAMETERS IN PATIENTS WITH CHRONIC PROSTATITIS В. В. Шухтин 1 , В. Н. Скнарь 2 , І. М. Шухтіна 2 , В. А. Жуков 3 V. V. Shuhtin 1 , V. N. Sknar 2 , I. N. Shuhtina 2 , W. Zukow 3 1 ГП «Украинский научно-исследовательсий институт медицины транспорта» 2 Одесский национальный медицинский университет 3 Uniwersytet Kazimierza Wielkiego, Bydgoszcz 1 SE Ukrainian Scientific Research Institute of Transport Medicine, Ministry of Health of Ukraine, Odessa 2 Odessa National Medical University, Odessa 3 Kazimierz Wielki University, Bydgoszcz Abstract Chronic prostatitis, inflammatory disease of infectious origin with the possible accession of autoimmune and dysbiotic violations occur in almost 50% of men of working age. The aim of the study was to determine the level of biochemical markers of inflammation and protective systems in the two biological fluids - blood serum and in seminal fluid of patients with chronic prostatitis. Studies have been conducted in 15 patients with chronic prostatitis and 12 healthy individuals (males aged 20-45 years with no systemic diseases). The results show a decrease in somatic nonspecific immunity and the level of physiological antioxidant system, as well as the leading role of non-infectious factor in the development of chronic prostatitis. Determination of biochemical markers of the above will contribute to the improvement of the efficiency of diagnostic and pathogenetic therapy of this disease. Keywords: chronic prostatitis, biochemical markers, diagnosis. Реферат Хронический простатит, воспалительное заболевание инфекционного генеза с возможным присоединением аутоиммунных и дисбиотических нарушений, встречается почти у 50% мужчин трудоспособного возраста. Целью исследования явилось определение уровня биохимических маркеров воспаления и защитных систем организма в двух биологических средах - сыворотке крови и в семенной жидкости у больных хроническим простатитом. Исследования были проведены у 15 больных хроническим простатитом и у 12 здоровых лиц (мужчины в возрасте 20-45 лет без соматических заболеваний). Результаты свидетельствуют о снижении общесоматического неспецифического иммунитета и уровня физиологической антиоксидантной системы, а также о ведущей роли неинфекционного фактора в развитии хронического простатита. Определение показателей вышеуказанных биохимических маркеров будет способствовать усовершенствованию алгоритма диагностики и эффективности патогенетической терапии данной патологии. Ключевые слова: хронический простатит, биохимические маркеры, диагностика.
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