Search Papers Chemical Journal of Chinese Universities-chinese | VOL. 37
Read
海洋来源真菌 Penicillim grisefulvum 中桔霉素类化合物的分离及抗菌活性
Publication Date Jun 27, 2016
Abstract
以海洋来源青霉真菌 Penicillim grisefulvum 为研究对象, 采用硅胶 、 C 18 柱和Sephadex LH-20凝胶柱层析等手段, 从中分离获得3个桔霉素类化合物: 7-methyl-penicitrinone A (1), citrinin (2) 和penicitrinone A (3), 其中化合物 1 为新化合物.通过一维核磁共振谱 (1D NMR) 、 二维核磁共振谱 (2D NMR) 和高分辨质谱 (HR-ESI-MS) 对化合物 1 的平面结构和相对构型进行确定, 并运用电子圆二色光谱 (ECD) 和量子化学计算方法确定了其绝对构型.抗菌活性测试结果表明, 化合物 1 对副溶血性弧菌 (Vibrio parahemolyticus) 表现出了较强的抑制活性 (MIC = 0.8 μmol/L), 高于阳性对照药物环丙沙星的活性 (MIC = 1.3 μmol/L).
ConceptsPowered By
Recommended Papers
AI-powered Research feed
Powered by
Introducing Weekly Round-ups!Beta
Powered by 
Round-ups are the summaries of handpicked papers around trending topics published every week. These would enable you to scan through a collection of papers and decide if the paper is relevant to you before actually investing time into reading it.
Climate change Research Articles published between Jun 20, 2022 to Jun 26, 2022
Jun 27, 2022
Articles Included: 2One eighth of the bird species in the world is considered globally threatened; the avifauna of Iraq comprises 409 species and is considered as the maj...
Read More
COVID-19