Abstract
Under conditions of omeprazole-induced hypergastrinemia the activity of NOS and the concentration of NO2-, the end product of metabolism of nitric oxide were studied in salivary glands of rats. We detected an increase in NOS activity, reaching a maximum (7.61+/-0.39 Mmol [NO2-]/(g*min) at 14th day of the experiment. At 28th day following omeprazole introduction its activity was 5,76+/-0.25 Mmol [NO2-]/(g*min).
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