Abstract
In this research, new derivatives of bicyclic fused rings containing bridgehead nitrogen atom imidazo/benzothiazole were prepared from 2-aminobenzothiazole with 2-bromo-1-(4-bromophenyl)ethan-1-one to form compound A1. Then, through the Mannich reaction, compound A2 was prepared from compound A1 with formaldehyde and 4-aminoacetophenone. Schiff bases A3-A6 were prepared from condensation reaction between compound A2 with different amines. Finally, the reduction reaction was accomplished by using NaBH4 to reduce the imine group to forming new compounds A7-A10. These compounds were characterized by FTIR, 1HNMR, and 13CNMR. The prepared compounds showed biological activity against some microorganisms.
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