Abstract
To assess correlation between inflammatory markers and heart rhythm disturbances in patients with coronary artery disease (CAD) and arterial hypertension. Design and methods. We examined inflammation markers - tumor necrosis factor alpha (TNF) and C-reactive protein (CRP) - in 80 patients. Results. The level of inflammatory markers was higher in hypertensive patients with heart rhythm disturbances and CAD. Heart rhythm disturbances in hypertensive patients and in patients with CAD was associated with elevated inflammatory markers - TNF and CRP. In patients with CAD and arrhythmia CRP level was 12,41 ± 0,92 mg/l, and TNF was 10,58 ± 0,71 pg/ml. TNF level in hypertensive patients with heart rhythm disturbances was 5,4 ± 0,49 pg/ml, and CRP level was 10,4 ± 0,92 mg/l. CRP and TNF levels significantly differed compared to healthy people (CRP - 3,74 ± 0,58 mg/l, TNF - 2,27 ± 0,53 pg/ml, p < 0,005).
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