Abstract
To investigate the cosmetic effects of drumstictree (Moringa oleifera, leaf) extract on skin care, we measured antioxidant and antimicrobial activities, tyrosinase and elastic activity inhibition. B16F10 melanoma cell has been used to measure cell viability. It was 42±2.66 mg/g GAE base and 16.5±1.7 mg/g Naringin base as a measurement result of total polyphenol and total flavonoid contents. DPPH free radical scavenging activity was 89% in a concentration at 500 μg/mL. Drumstic-tree (Moringa oleifera, leaf) extract exhibited in vitro antimicrobial activity against MRSA CCARM3115. EtOH extract of Moringa oleifera showed 25.1% (L-Tyrosine) and 20.1% (L-DOPA) of tyrosinase inhibition, respectively. In elastase inhibition assay, EtOH extract of Moringa oleifera showed 29.6% of inhibition. At a concentration of 200 μg/mL, tyrosinase and elastase activation were found to inhibited dose-dependent. These results suggest EtOH extract from Moringa oleifera has excellent activities in the antiwrinkle and whitening. Therefore, it expected to be used effectively for development of functional cosmetic materials.
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