Abstract

New insights into the mechanisms underlying the action of macro- and trace elements on the brain and the microbiota-gut-brain axis will promote the development of food interventions aimed at optimizing brain function and preventing or treating neurodegenerative disorders and other age-related conditions. Rehabilitation of the seven most common deficiencies of trace elements: iron, zinc, copper, selenium, cobalt, chromium and iodine can increase global IQ, cognitive brain neurocommunication and the intellectual development of Homo sapiens in the 21st century. Further structural-functional and cognitive development of the brain will require quantitative and qualitative provision of new tools of bioelementology and brain nutritionology. N. P. Romanchuk studies show that for new neurogenesis and neuroplasticity, to manage human neuroplasticity and biological age, for modern neurophysiology and neurorehabilitation of cognitive impairment and cognitive disorders, sufficient functional and energy nutrition of the brain is needed. Authors’ works in the creation of a new protective functional and epigenetic nutrition, the clinical application of strategic combined and hybrid methods and tools in the neurorehabilitation of the circadian system, the use of artificial intelligence in the functioning of the “cognitive brain” and “visceral brain” and brain-microbiota neural networks are a promising applied direction in personalized medicine. Psychoneuroimmunological communications and neuroendocrinological multimodal methods make it possible to significantly increase the duration of an active and high-quality healthy life of a person. Modern communications are multilevel, multi-paradigm and interdisciplinary models of information exchange. The new competencies of psychoneuroimmunoendocrinology and neuroeconomics play a strategic role in interdisciplinary science and interdisciplinary planning and decision-making, in creating a fundamentally new theory that will explain our decisions with genes, neuronal activity, our brain's perception of information, the influence of neurosociology and neuroevolution.

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