ГІСТОЛОГІЧНА ДІАГНОСТИКА ХРОНІЧНОЇ НИРКОВОЇ НЕДОСТАТНОСТІ В КОТІВ

Abstract

The objective of the study is to set the criteria of histological diagnosis of chronic renal insufficiency in cats. Lifetime diagnosis of chronic renal failure in a complex was set in complex, basing on anamnesis, clinical signs and laboratory results of blood and urine. For histological studies 29 cats corpses of different breeds and ages were used, who died from chronic kidney failure. Paraffin sections of 7 – 10 mm thickness from the different segments of kidney were stained with Carazzi's hematoxylin and eosin.It was established that during the histological studies in the kidney of cats who died from chronic kidney failure the microscopic changes diversity is characteristic. A characteristic feature of chronic kidney failure cats is complex of changes, which includes: 1) expand and overflow of blood capillaries of the glomeruli; 2) sludge–phenomenon in the capillaries of the glomerulus; 3) lack of blood in the capillaries of the glomerulus; 4) an increased amount of leachate in the cavity of Boumen–Shumlyanskiy capsule; 5) thickening (in some casescrescent–like) of parietal layer of Boumen–Shumlyanskiy capsule due to the hypertrophy and hyperplasia of its cells in the part of kidney cells; 6) glomerular sclerosis of the renal corpuscles and total necrosis of the renal corpuscles; 7) microcysts formation, mainly in the cortex. Other microscopic changes in different animals vary.