여성 노인의 근감소성 비만과 대사증후군 위험인자 간의 연관성 검증

Abstract

This study examined the association with sarcopenic-obesity and metabolic syndrome risk factors in elderly women. This was a cross sectional study involving 261 elderly women (aged 74.0±6.9 years). Total body composition analysis was performed with a dual-energy X-ray absorptiometry (DXA). Measured metabolic risk factors included waist circumference (WC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), fasting blood glucose (FBG), systolic (SBP) and diastolic blood pressure (DBP). Using the cut-off values of the Asian Working Group for Sarcopenia (AWGS) study and body mass index (BMI), subjects were classified as subgroups of normal, sarcopenia, obesity, and sarcopenic-obesity. One-way ANOVA followed by a LSD post-hoc test was used to compare any group differences in measured variables among the sarcopenic-obesity based subgroups. Logistic regression analyses were used to determine the odds ratio (OR) of sarcopenic-obesity status for having metabolic syndrome. There were significantly increases for WC, TG, SBP and decrease HDL-C across incremental sarcopenic-obesity status. Compared with the normal group (reference group, OR=1), the sarcopenia group (OR=2.53), obesity group (OR=3.99), and sarcopenic- obesity group (OR=5.56) had significantly higher ORs for having metabolic syndrome. The findings of this study suggested that healthy diet, and regular exercise should be promoted for sarcopenic-obesity that is important factor to prevent metabolic syndrome in elderly women.