Abstract

Abstract. Introduction. The article considers the study results of the metabolic syndrome effect on the state of periodontal tissues in persons with mental disorders depending on the duration of the disease and the use of antipsychotics. Material and methods. In the Republic Clinical Psychiatric Hospital named V.M. Bekhterev of the Ministry of Health of Tatarstan Republic (Kazan) 206 patients who were treated for schizophrenia were examined. Depending on duration of disease, all patients were divided into three groups: 1 group with less than 5 years - (88 people), 2 group - from 5 to 10 years (73 people) and 3 group - more than 10 years (45 people). According to the analysis of medical records of inpatients, comorbidities were studied, the study included patients with cardiovascular diseases and diabetes mellitus. Recent indicators of systolic blood pressure, diastolic blood pressure, body mass index, fasting blood glucose index, low-density lipids, high-density lipids were recorded, a dental history and complaints were collected, and oral examination according to generally accepted criteria. For statistical results, a package of statistical programs SPSS 13.0. Results and discussion. It was revealed that diseases incidence of cardiovascular system, diabetes mellitus, systolic and diastolic blood pressure, glucose in the blood and low-density lipids significantly increased and positively correlated, depending on length of the patient's illness. The level of high-density lipids, while, on the contrary, decreased. Body mass index was the highest in the group of patients with 5 to 10 years of age experience and then tended to decline. The study identified a high prevalence of severe periodontitis in persons with mental disorders with 5 to 10 years of disease experience. With a severe degree of periodontitis, bleeding of the gums increased, these pathological changes were noted when the patient had a history of cardiovascular pathology and directly correlated with the level of systolic blood pressure, blood glucose and low-density lipids. Conclusion. The close association of periodontal conditions and manifestations of metabolic syndrome in persons with mental disorders suggests the need for an integrated approach to the treatment of oral diseases and a wide interdisciplinary interaction.

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