Abstract
We studied the level of spontaneous post-traumatic recovery of motor function in male FVB mice. The left-side spinal cord hemisection was a model of damage. The locomotor activity and spasticity of the hindlimb were determined using the BBB and B scales and the Ashword scale during the first 12 weeks of the post-traumatic period. According to the results of the experimental study, at a later date in the post-traumatic period, the restoration of the function of the hind limb was observed at the level of 3.22 ± 0.46 points (out of 21 possible) on the BBB scale and 1.88 ± 0.27 points (out of 9 possible) on the B scale. Such indicators of hind limb locomotor activity conform to the phase of early recovery. However, at all studied time intervals after spinal cord injury, a consistently high level of hindlimb spasticity in experimental animals was noted – 3.17 ± 0.46 (out of 4 possible) on the Ashword scale.
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