ВНУТРИПОЛОСТНОЕ ВВЕДЕНИЕ МЕТОТРЕКСАТА В КОМПЛЕКСНОЙ ТЕРАПИИ ПРОСТЫХ КИСТ ЩИТОВИДНОЙ ЖЕЛЕЗЫ

Abstract

The development and implementation of new more effective minimally invasive technologies for the treatment of simple thyroid cysts is current. evaluating the effectiveness of a method of treating simple thyroid cysts involving echo-assisted puncture, evacuation of contents and subsequent introduction of methotrexate into a cavity. The results of examination and treatment of 67 patients suffering from thyroid cysts are presented. Asymptomatic flow was noted in the majority of 61 (91.04%) patients, 4 (4.99%) - noted swallowing, and 2 (2.97%) - difficulty swallowing. For the first time, 42 (55.26%) patients independently identified their education, and 34 (44.74%) during a preventive medical examination. When echo-examined, all patients showed cystic thyroid masses, the average size of which was 20.8±8.3 mm. Outpatient in aseptic conditions under the control of ultrasound, puncture aspiration of the contents was carried out and subsequent intra-cavity administration of methotrexate solution with a cytostatic content of 20 mg to 30 mg. The volume of methotrexate introduced corresponded to the amount of aspirated liquid - 11.9 ± 3.8 ml (range from 2.5 to 16.2 ml). With control sonography, performed a month after the intervention in 51 (76.12%) cases, cystic formation was not visualized, in 5 (7.46%) - the maximum size of the latter did not exceed 9 mm, in 11 (16.42%) cases - the cavity decreased by no more than one third. After 12 months with a control ultrasound, all cystic masses underwent regression: in 61 (91.04%) cases, no masses were echo-visualized, in 3 (4.48%) - the maximum size of the latter did not exceed 9 mm. High efficiency (no formation or reduction of the latter to 9 mm) in 95,52% of cases is echo-proved.