Abstract
Poultry is one of the most intensive and dynamic sectors of agricultural production, it is an avantgarde industry not only in animal husbandry, but also in all agriculture. However, various infectious diseases do not bypass this industry. The problems of industrial and private poultry farming are such diseases of poultry as pasteurellosis, colibacteriosis, salmonellosis, staphyllococcosis. The development of new treatments for these diseases is an urgent trend in modern veterinary medicine, which includes preclinical trials, and in particular the assessment of the tolerability of the drug. We conducted studies of the combined antibacterial drug Dithrim® OR. It has been established that oral use of Ditrim® OR in a therapeutic and three-fold therapeutic dose does not have a pronounced pathological effect on the body of broiler chickens. During the experiment, no bird death or clinical signs of intoxication (depression, diarrhea, etc.) were noted. The bird was active and well-fed. The live weight of chickens in the experimental groups did not significantly differ from the weight of the bird that was kept in the control group. It has been found that the preparation at the specified doses, duration and method of use does not adversely affect the body of broiler chickens and is well tolerated by animals.
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