Функциональные расстройства желудочно- кишечного тракта у детей дошкольного возраста: современные подходы к терапии

Abstract

Recurrent abdominal pain (RAP) syndrome is a common pathology of childhood, which is often encountered in pediatric outpatient practice. Currently, pharmacological options are insufficiently developed, in this regard, we decided to use the drug trimebutin in the form of powder for preparation of suspension for oral administration for the treatment of this group of patients. Objective. To evaluate the effect of trimebutine therapy in the form of powder for preparation of oral suspension on the course of pain syndrome and a number of associated symptoms in preschool patients with functional RAP syndrome. Patients and methods. The study included 84 children aged 3 to 5 years who applied to the consultative and diagnostic clinic "Gastroenterological Center" (Ufa, Republic of Bashkortostan). The diagnosis of functional gastrointestinal disorders (FGD) was established in 53 patients (63.1%) of the total number of patients aged 3 to 5 years with RAP. Results. Complete disappearance of symptoms occurred in 48 (90.5%) outpatients. Commitment to treatment was high in the majority of patients (73.6%, 39 children), which, among other things, ensured high efficacy of the therapy. Conclusion. Trimebutin in the form of powder for suspension preparation in our study showed excellent efficacy in the management of RAP syndrome and associated symptoms, which is extremely valuable for determining the tactics of therapy of this pathology in preschool children in pediatric practice. The drug was well tolerated by patients, which ensured high adherence to treatment. Key words: recurrent abdominal pain, functional gastrointestinal disorders, functional dyspepsia, irritable bowel syndrome, functional gallbladder disorder, sphincter of Oddi dysfunction, functional abdominal pain, trimebutin, Trimedate