Abstract
Within the framework of this study, a quantitative HPLC-MS/MS (high-performance liquid chromatography with mass spectrometric detection) method for the determination of vancomycin was developed. The method for the quantitative determination of vancomycin in human plasma was validated using the chromato-mass spectrometric method. The method was validated in accordance with the requirements of the EAEU for bioanalytical methods. The validated analytical range of thetechnique was 1–100 μg/mL in plasma.
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