Abstract
Background. The dynamics of cortisol, thyroid-stimulating hormone (TSH), thyroxine (T4) in radical mastectomy (RM) has not been sufficiently studied. Objective. Determine the dynamics of the content of cortisol, TSH and T4 in patients with RME using two methods of anesthesia. Metherial and Methods. 52 patients underwent RM. Anesthesia in group 1 (n=14) - general anesthesia (GA), in group 2 (n=38) - GA and paravertebral blockade (PVB). The study was conducted in 4 stages: 1 - admission to the operating room; 2 - 30 min after the start of the operation; 3 - 2 h after the operation; 4 - 20-24 h after surgery. Results. In groups 1 and 2, cortisol levels increased in step 3 (p 0,05). Conclusion. In the conditions of GA with PVB, an increase in TSH is 1.55 times. When RM in the conditions of GA and GA with PVB, the content of cortisol does not increase.
Highlights
The dynamics of cortisol, thyroid-stimulating hormone (TSH), thyroxine (T4) in radical mastectomy (RM) has not been sufficiently studied
Лан вывод о том, что отсутствие интраопераци- При сравнении содержания Т4 между группами онного повышения содержания кортизола явля- отсутствовали различия на всех четырех этапах ется показателем адекватного уровня анальгезии наблюдения (р>0,05)
Во время радикальной мастэктомии в условиях многокомпонентную сбалансированную эндотрахеальную анестезию (МСЭА) в комбинации с паравертебральная блокада (ПВБ) отмечено интраоперационное повышение содержания ТТГ до 1,55 раза по сравнению с исходным
Summary
The dynamics of cortisol, thyroid-stimulating hormone (TSH), thyroxine (T4) in radical mastectomy (RM) has not been sufficiently studied. Тиреотропного гормона (ТТГ), тироксина (Т4) в плазме крови при радикальной мастэктомии (РМ) изучена недостаточно. Определить динамику содержания кортизола, ТТГ и Т4 у пациентов при РМ с применением двух методов анестезиологического обеспечения.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
