Abstract

In patients with isolated arterial hypertension (AH) and in combination with chronic obstructive pulmonary disease (COPD+AH) we have studied indicators of daily monitoring of blood pressure (BP) and analyzed relationship of these parameters with markers of inflammation (interleukin-1β, tumor necrosis factor α) and oxidative stress (malonicdialdehyde, catalase). In the group of patients with combined pathology of COPD+AH it was established the presence of higher indicators of BP daily monitoring, the prevalence of pathological variant of BP circadian profile - nondippers and the increase in frequency of the BP circadian profile - nightpeakers. Patients with COPD+AH with circadian diastolic BP of nondippers and nightpeakers types had significantly higher levels of inflammatory markers, and lower catalase activity in blood as compared to persons with circadian diastolic BP of dippers type

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