Abstract
The article presents the analysis of efficiency of skin test with tuberculous recombinant allergen (TRA, diaskintest), as a screening method for tuberculous infection in children and adolescents above 8 years old using Penza Region as an example. In 2016, 112,808 persons were screened with TRA test, 97.5% of children were covered with this test. TRA test proved to be effective for detection of tuberculosis in children and adolescents. When TRA test is used, less than 1% respond positively to it among those screened on a regular basis (in 2015 – 0.97% and in 2016 – 0.86%). The differential approach to the prescription of preventive treatment in risk groups significantly increases the motivation of 92.0% of parents to have it. With a positive result of TRA test, the screening for tuberculosis with this test and multispiral computer tomography of the chest significantly improve the structure of clinical forms of tuberculosis in children and adolescents due to an increase of the number of limited lesions with minimal manifestations.
Highlights
The article presents the analysis of efficiency of skin test with tuberculous recombinant allergen (TRA, diaskintest), as a screening method for tuberculous infection in children and adolescents above 8 years old using Penza Region as an example
In 2016, 112,808 persons were screened with TRA test, 97.5% of children were covered with this test
TRA test proved to be effective for detection of tuberculosis in children and adolescents
Summary
Это дети в возрасте 8 лет, имевшие ранее сомнительные реакции на пробу Манту для отбора на ревакцинацию БЦЖ, и дети, родители которых отказались от постановки пробы с АТР. В целом охват иммунодиагностикой туберкулеза у детей и подростков в возрасте 8-17 лет составил 97,5%. По результатам постановки кожных проб формировались группы риска среди детей и подростков, подлежавших углубленному обследованию у фтизиатра для исключения локального туберкулеза, обнаружения латентной туберкулезной инфекции и нуждающихся в проведении превентивного лечения и динамическом наблюдении. - VIА группа диспансерного учета (ГДУ): дети с положительными реакциями на АТР, при ретроспективном анализе туберкулинодиагностики которых в предыдущие годы не регистрировалось виража туберкулиновых проб (переход отрицательной или сомнительной реакции на пробу Манту с 2 TE в положительную, не связанную с иммунизацией вакциной БЦЖ). Все полученные результаты внесли в специально разработанную таблицу и обработали с помощью компьютерной программы Microsoft Excel
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